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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1046 | Mexiletine hydrochloride | KOE-1173 (hydrochloride),Mexiletine HCl,KO1173 | AhR , Sodium Channel |
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myoca... | |||
T1879 | 3-Methyladenine | 3-MA,NSC 66389 | Mitophagy , PI3K , Endogenous Metabolite , Autophagy |
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM). 3-Methyladenine inhibits autophagy. | |||
T32030 | GYKI-16638 HCl | GYKI 16,638,GYKI16,638,GYKI-16638,GYKI-16,638,GYKI16638,GYKI 16638 | |
GYKI-16638 is a novel antiarrhythmic agent that demonstrates combined class IB and class III antiarrhythmic properties in human ventricular muscles, similar to the electrophysiological findings after chronic amiodarone t... | |||
T12023 | Mexiletine-d6 hydrochloride | KOE-1173 D6 hydrochloride,Mexiletine D6 hydrochloride | Others |
Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic. | |||
T21427 | Mexiletine | Mexitil,Mexiletene,KO-1173,KO1173,KO 1173 | |
Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat musc... |